Unique IS2 (B. coagulans), earlier known as Lactobacillus sporogenes is a Lactic Acid Bacteria (LAB). It is gram positive, spore forming bacterium. It is non-pathogenic and safe for human consumption with self-affirmed GRAS. It is naturally encapsulated therefore is a tough and stable probiotic.
Bacillus coagulans or Lactobacillus sporogenes is a high-temperature tolerant strain unlike most of the other probiotic strains. Therefore it doesn’t need refrigeration and is shelf-stable.
It is a gram-positive, facultative anaerobic, non-pathogenic, spore-forming, lactic acid-producing bacteria. These probiotic bacteria are able to withstand harsh conditions, like acidic pH in the stomach, and are very effective in maintaining overall gut health (3).
Gut health
Management of Irritable Bowel Syndrome (IBS)
B. coagulans Unique IS-2 reduces abdominal pain and increases the number of complete spontaneous bowel movements. It exhibited significant improvements in abdominal discomfort, bloating, urgency, incomplete evacuation, straining, passage of gas, bowel habit satisfaction, overall assessment of IBS symptoms, and the total score (4).
Reduces the Severity of Diarrhea
B. coagulans Unique IS-2 to alleviate diarrhoeal symptoms. A clinical trial was carried out on 28 adults suffering from acute diarrhea. At the end of the study, the duration of diarrhea decreased from 35 mins to 3.5 mins per day and the frequency of diarrhea is aslo decreased from 7.96 to 0.76 times per day. Improvement in abdominal pain and consistency of stool has been observed (5).
Immune health
A study was carried out on 68 adults aged 58-67 years old to evaluate the effect of Uniue IS-2 on immune health. Natural killer (NK) cell activity was assessed. At the end of the study, NK cell activity improved significantly in individuals consuming B. coagulans Unique IS-2 group as compared to other groups. It was found that 56% of individuals in Group 3 experienced over 200% improvement in NK cell activity compared with other groups. This result shows that B. coagulans Unique IS-2 has a role in enhancing immune response (6).